The cult of Asclepius emerged in the late fifth century BCE. Arguably, the spread of this religion is as significant to the history of medicine as the contemporaneous developments around the Greek physician Hippocrates (ca. 460–ca. 375 BCE).
While many gods were ascribed healing powers and people frequently prayed to different deities for relief from illness, Asclepius did not belong to the original canon of Greek deities. Though a relative latecomer, he quickly came to symbolize the power of divine healing and the medical art itself: healing gods were not usually a distinct category of deity, making Asclepius unique in his specialization. An abundance of coins minted in the Roman Empire bearing Asclepian iconography illustrates his ongoing importance in the first three centuries CE. Tellingly, his snake-entwined staff remains an icon of medicine even today.
Mythological accounts of Asclepius’s origins vary and occasionally conflict. It was widely believed that he was the son of the god Apollo and a mortal woman, Coronis. Apollo, himself a god associated with healing, first taught Asclepius about medicine; the centaur Chiron then guided his formal education in the discipline.
While scholars debate the origins of Asclepius, there is no doubt about how rapidly his cult expanded. The epicenter of the cult was in Epidaurus, his reputed birthplace, but, already by 420 or 419 BCE, a sanctuary to the god stood on the south side of the Acropolis in Athens, and the playwright Sophocles produced a paean in the god’s honor; by the third century BCE, the cult had arrived as far away as Rome, imported in the hope of driving away an outbreak of plague. The worship of Asclepius coexisted with other beliefs; over the course of centuries, the god easily syncretized with other deities, sometimes even superseding them.
Asclepius then visited the physician in his sleep and advised him to cut the artery between his index and middle fingers. Galen followed the god’s instructions, adjusted his diet, added exercise at the gymnasium—and enjoyed good health for decades afterward. Galen was not shy about his devotion to Asclepius, telling the emperor Marcus Aurelius: